Products Catalog
| Transfection | ||
| 00-0001 | Stemfect™ DNA Plasmid Transfection Polymer Stemfect™ is a novel polymer specifically designed to transfect plasmid DNA into stem cells. It enables 2-5X improved transfection efficiency compared to Lipofectamine™ 2000. Lipofectamine™ is a trademark of Invitrogen Corporation. | 5x100μl + 30 ml buffer $199.00 |
| Reprogramming | ||
| 00-0002 | RiPStem™ Retroviral Mouse Plasmid Set The RiPStem™ Retroviral Mouse Plasmid Set contains four retroviral backbone plasmids, each containing one of four transcription factor cDNAs (Oct4, Sox2, Klf4, and c-myc) under the control of the viral promoter. | 4x2μg (100ng/μl) $599.00 |
| Cytokines | ||
| 03-0001 | Stemfactor™ Activin A (Human Recombinant) Stemfactor™ Activin A is a crystallography-grade preparation providing the highest purity available. Activin A is bi-modal in action having been shown to maintain pluripotency of stem cells1 and promote differentiation2. 1. Beattie et al., Stem Cells 23:489-495 (2005). 2. Vallier et al., Cell Science 118:4495-4509 (2005). | 5ug $179.00 |
| 03-0002 | Stemfactor™ Fibroblast Growth Factor-basic (Human Recombinant) Stemfactor™ Fibroblast Growth Factor-basic (Human Recombinant) bFGF is a critical component of embryonic stem cell culture medium because it is necessary for the cells to remain in an undifferentiated state. | 50μg $99.00 |
| 03-0003 | Stemfactor™ Epidermal Growth Factor (Human Recombinant) Epidermal Growth Factor (EGF) is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation of a wide range of epidermal and epithelial cells. | 100μg $79.00 |
| Small Molecules | ||
| 04-0001 | Stemolecule™ RG108 Stemolecule™ RG108 is the highest purity preparation available, only from Stemgent. RG108 is a cell-permeable, specific DNA methyltransferase inhibitor that displays anti-proliferative properties with no detectable cytotoxic effects1. 1. Brueckner, B., et al, Cancer Res. 65, 6305-6311 (2005) | 10mg $129.00 |
| 04-0002 | Stemolecule™ BIX01294 BIX01294 enhances reprogramming efficiency of neural progenitor cells to the same levels as when four transcription factors (Oct4, Klf4, Sox2 and c-Myc) were introduced to somatic cells1. 1. Shi, Y. et al., Cell Stem Cell, 2:525-528 (2008). | 5mg $99.00 |
| 04-0003 | Stemolecule™ BIO BIO is the first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells1. 1. Sato, N. et al., Nat Med 10:1, 55–63 (2004). | 2mg $99.00 |
| 04-0004 | Stemolecule™ CHIR99021 Self-renewal of embryonic stem cells is enabled by inhibition of GSK3β along with the elimination of differentiation-inducing signaling from mitogen-activated protein kinases. CHIR99021 has been used to block the activity of GSK3β1. 1. Ying Q.-L. et al., Nature 53:519-523 (2008). | 2mg $139.00 |
| 04-0005 | Stemolecule™ Sodium Butyrate In cultured mouse and human cells, sodium butyrate has been shown to inhibit both the mRNA and protein content of cyclin D11. Sodium butyrate is a known inhibitor of histone deacetylases2. 1. Lallemand, F. et al., Biochem. Biophys. Res. Commun., 229(1):163-169 (1996). 2. Kruh, J., Mol. Cell. Biochem. ,42(2):65-82 (1982). | 500mg $49.00 |
| 04-0006 | Stemolecule™ PD0325901 PD0325901 has been shown to suppress ERK activation without side effects, which was sufficient to sustain efficient ES-cell self-renewal in combination with CHIR99021 only1.. Ying Q.-L. et al., Nature 53:519-523 (2008). | 2mg $139.00 |
| 04-0007 | Stemolecule™ Valproic Acid VPA has been shown to enhance iPS generation in a three-factor transduction (Oct4, Klf4 and Sox2) without introduction of the c-Myc oncogene1. 1. Huangfu, D. et al., Nat. Biotechnol., 2008, (published online June 22, 2008). | 5g $49.00 |
| 04-0008 | Stemolecule™ PD173074 Stemolecule™ PD173074 is a recent addition to Stemgent's expanding collection of small molecule stem cells tools. PD173074 inhibits the FGF signaling pathway leading to self-renewal of mouse embryonic stem cells, when combined with CHIR99021 and PD03259011 supplied by Stemgent. 1. Mohammadi, M. et al., EMBO J. 17:5896-5904 (1998). | 2mg $119.00 |
| 04-0009 | Stemolecule™ Purmorphamine Stemolecule™ Purmorphamine promotes the differentiation of human and murine mesenchymal progenitor cells into osteoblasts1,2. It is ideal for stem cell and cell signaling researchers using human embryonic stem cells to investigate differentiation with small molecules. 1. Wu, X. et al., J Am Chem Soc. 124:14520-14521 (2002). 2. Beloti, M. M. et al., Journal of Cell Biology International 29 (7):537-541 (2005). | 5mg $99.00 |
| 04-0010 | Stemgent™ SB431542 SB431542 has been shown to stimulate proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells via ALK receptor inhibition1,2. 1. Inman, G. J. et al., Mol. Pharmacol., 62:65-74 (2002). 2. Watabe T. et al., J. Cell Biol., 163(6):1303-1311 (2003). | 5mg $79.00 |
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